Feinberg School of Medicine
Professors | Associate Professors | Research Associate Professors | Assistant Professors
| Research Assistant Professors |
Professors -
Wayne F. Anderson (MPBC) - protein-nucleic acid interactions, protein-protein interactions, the complex realtionships between a protein's structure and its biological functions, structural genomics
Rex Chisholm (CMB) - dictybase is an online informatics resource for Dictyostelium; Disease Ontology - creation and maintenance of a comprehensive hierarchical controlled vocabulary for human disease representation
Kasturi Haldar (Pathology) - regulation of pathogenic vacuoles; pathogens including Salmonella, Mycobacteria, Chlamydia, and Toxoplasma; emerging genetic techniques to develop functional assays, mining databases for functional organelle protein motifs
Ann Harris (Pediatrics) - The main interests of the group centre on the basic defect in cystic
fibrosis (CF). We are tackling two important questions that are central to the pathology of the disease: First, what are the genetic elements that confer tissue specificity and temporal regulation
on expression of the CFTR gene, that when mutated causes CF? Second, why are CF respiratory and digestive systems obstructed by mucous secretions? Progress on these topics could make a
significant contribution to the efficacy of treatments for CF, either by gene therapy or by pharmacological means.
Jerilyn A. Logemann (School of Communication) - combinations of videofluoroscopic, manometric, videoendoscopic and electromyographic data collection techniques are used to study swallowing in normal subjects and patients with swallowing disorders; voluntary versus automatic neural control of specific neuromuscular components of the pharyngeal swallow by defining the biomechanics of oropharyngeal physiology during specific swallow types and voluntary maneuvers
Richard M. Longnecker (Microbiology-Immunology) - Epstein-Barr virus (EBV) transformation, latency, and entry; animal models of EBV latent infections
Hank Seifert (Microbiology-Immunology) - Molecular mechanisms of pilus antigenic variation in Neisseria gonorrhoeae
Marcelo Bento Soares (Pediatrics) - uncovering molecular mechanisms underlying genomic instability, aberrant transcription, and splicing in tumorigenesis and cancer metastasis; genome wide identification and epigenomic analysis of Natural Antisense Transcripts and transcriptionally active retro-transposable repetitive elements in cancer, their potential role in promoting tumor heterogeneity, and their value as molecular markers for diagnosis, prognosis, and early detection of cancer
D. Martin Watterson (MPBC) - using an interdisciplinary approach to study fundamental biological processes and mechanisms of pathophysiology has identified new approaches to therapeutic intervention in areas of unmet medical need, the approach centers around integrative chemical biology, medicinal chemistry, and computational biology interdigitated with molecular genetics and animal models of disease
Associate Professors -
Douglas M. Freymann (MPBC) - the structural biology of the heterodimeric GTPase core complex that mediates assembly of the of the co-translational protein targeting apparatus of the Signal Recognition Particle at the membrane; exploiting high resolution X-ray crystallography to understand the mechanisms by which interactions with ligands (GTP in this case) regulate protein function
Geoffrey S. Kansas (Microbiology-Immunology) - molecular biology of leukocyte adhesion and migration
Timothy M. Kuzel (The Robert H. Lurie Comprehensive Cancer Center) - development of Northwestern University's clinical trial informatics systems and expansion of the same; biological and experimental therapies of cancer; also researches hematologic malignancies and prostate cancer
Todd Parrish (Radiology) - The primary focus of the NU Neuroimaging Research Laboratory is the improvement and application of neuroimaging methods to better understand human brain function. Work in the lab draws from many disciplines such as biomedical engineering, physics, biophysics, statistics, electrical engineering, computer science, neuroscience, physiology, biology, and anatomy.
Research Associate Professors -
Borko D. Jovanovic (Preventive Medicine) - classical statistical methods and new computational and informatics realities in research and teaching
Warren A. Kibbe (The Robert H. Lurie Comprehensive Cancer Center) - biological data representations, biological ontologies, application of basic science technologies to clinical practice through IT systems
Assistant Professors -
Raymond C. Bergan (The Robert H. Lurie Comprehensive Cancer Center) - profiling gene expression of specific cell populations present within otherwise complex prostate tissue by microarry experiments
David M. Liebovitz (General Internal Medicine) - understanding the benefits of clinical decision support at the point of care and optimizing the use of electronic health information for patient care, research, and education
Denise M. Scholtens (Preventive Medicine) - development of methology for the analysis of high-dimensional data; analysis of factorial designed microarray experiments and local modeling of protein complexes; development of measurement error models for graph theoretic data and efficient sampling schemes for network data collection
Hans-Georg Simon (Pediatrics) - identification of genes that are active during the regeneration of limbs and/or hearts to determine genetics pathways that are operational in regenerating animals but not in mammals; identify how the same transcription factors orchestrate different functional activities
Joshua Singer (Ophthalmology and Physiology) - Night, or scotopic, vision represents a remarkable feat of signal processing: a small signal generated by the absorption of only a few photons by an array of thousands of photoreceptors generates a visual response. In mammals, a specialized neural circuit called the rod pathway mediates night vision. Although anatomically well-characterized, little is known about the nature of signal transfer between its component neurons. Dr. Singer's laboratory studies how the output of rod photoreceptors is passed across multiple synapses without being degraded by studying the physiology of the second synapse in the rod pathway.
San Ming Wang (Center for Functional Genomics) - genome science: SAGE (serial analysis of gene expression), GLGI (generation of longer 3' cDNAs from SAGE tags for gene identification), digital karyotyping, GIS, and cDNA microarray analysis of disease
Research Assistant Professors -
Simon Lin (The Robert H. Lurie Comprehensive Cancer Center) - extracting biomedical knowledge from high-throughput data collections using database, data mining, and statistical methods; computational systems to analyze mass spectrometry data; testing hypothesis that a wavelet-based framework is more effective than traditional analyses